Homozygous Hemoglobinosis CC: A Series of 3 Cases and a Review of the Literature

نویسندگان

چکیده

Hemoglobinosis C occurs mainly in Africa and America with a high frequency West Africa. In Senegal, homozygous hemoglobinopathy CC constitutes very rare profile of which only 3 cases are followed the clinical hematology department Dakar. The 1st case is 49-year-old female patient, notion degree consanguinity, long history abdominal pain who presented poorly tolerated anemic syndrome splenomegaly. biological assessment showed moderate anemia (7.6 g/dL) microcytic hypochromia (HbC = 99.2%; HbA2 0.8%) on hemoglobin electrophoresis. second was 22-year-old patient 2nd consanguinity Chauffard triad. haemogram mild anaemia (11 g/dL), hypochromic. Hemoglobin electrophoresis confirmed 95.3%; 4.7%). third 27 years old, diffuse consanguinity. haemoglobin 94.6%; 5.4%). negativity Emmel test front this presentation suggestive sickle cell disease means that type diagnosed late our regions. We therefore recommend systematic performance presence any chronic hemolytic anemia.

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ژورنال

عنوان ژورنال: Open journal of blood diseases

سال: 2023

ISSN: ['2164-3180', '2164-3199']

DOI: https://doi.org/10.4236/ojbd.2023.131002